Unmetabolised Folic Acid

Folic acid is a synthetic form of vitamin B9 or folate. Unmetabolised folic acid appears in the serum when the folic acid taken either in food fortification or supplements is not metabolised by the body and therefore elevates as it has nowhere to go.

Although research is not conclusive, there are studies implicating unmetabolised folic acid with cancer, autism, reduced DNA methylation, increase in uracil misincorporation. It is important as practitioners that we understand the implications of this and which patients may be more at risk than others.

Here are some of the best bits we covered:

 Folate metabolism.
 Why folic acid cannot be metabolised the same way as methyl folate or folinic acid?
 What are the adverse effects of a high level of unmetabolised folic acid.? I.e. studies show that it is linked to:

• Cancer
• Autism
• Reduce natural killer cell activity
• Reduced DNA methylation
• Increased uracil misincorporation
  

 How long does it take to remove folic acid from the body after you stop eliminating it from food and supplements?
Methyl folate cannot build up like unmetabolised folic acid, why is this?
Why is it important to be able to evaluate and consider the form of folate that we use.

Want complimentary and unlimited access to this video?
Become a Methylation and Genomics member today! For only AUD $97.00 (+ GST if applicable) per month or just AUD $899.00 per year on our best-value annual membership plan, you will have access to our Methylation and Genomics Institute courses, webinars and clinic resources. You will join our savvy practitioner community in our monthly deep dive sessions, Q&A sessions and much more. Don't miss out! Click here to join now!

Need help?
E-mail: enquiries@mthfrsupport.com.au

Privacy & Security
Your privacy is important to us, we will not share, sell, or trade online information that you provide to us. All personal information you submit is encrypted and stored securely.