Endometrial Microbiome: Unveiling its Role in Endometriosis Management Presented by Viviane Casaroli

"Endometrial Microbiome: Unveiling its Role in Endometriosis Management”

 Presented by Viviane Casaroli

Viviane Casaroli began her career working in the Microbiology lab at the University of São Paulo (2011-2015), where she cultured opportunistic pathogenic bacteria and researched genetic regulatory mechanisms related to biofilm formation and secondary metabolite synthesis during her undergraduate studies. In 2018, she earned a Master of Science from the Tokyo Institute of Technology and pursued a PhD at the same institute from 2019 to 2020, where she focused on bioengineering microorganisms for green polymer production. In 2020, she made the decision to transition into the biotech industry, joining Igenomix (now part of the Vitrolife Group) as a scientific advisor and account manager for APAC. In this role, she currently assists in developing and communicating new clinical, evidence-based information to colleagues, fertility specialists, and IVF patients across the Asia-Pacific region.

Summary:

Once thought to be sterile, the human uterus has been demonstrated to harbor a unique microbial community which differs in composition and physiological condition from that in the vagina. In this presentation, we will explore the significant role of the endometrial microbiota in human reproduction. We will navigate recent data highlighting the composition and diversity of the human endometrial microbiota, emphasizing its potential influence on reproductive health.

Additionally, we will compare traditional diagnostic methods with modern molecular approaches for diagnosing chronic endometritis, discussing their respective advantages and limitations. Traditional methods often rely on visual techniques which depend on the skill of the evaluator, while molecular techniques offer a more comprehensive view of microbial communities.

Finally, we will examine the impact of the endometrial microbiota on clinical outcomes, particularly in patients undergoing in vitro fertilization (IVF) treatments. Understanding the interplay between the endometrial microbiota and reproductive processes can provide valuable insights into improving IVF success rates and overall reproductive health.

Key Speaking Points:

1. Review of recent data on the human endometrial microbiota.
2. Comparison of traditional and molecular approaches to diagnose chronic endometritis.
3. To investigate how the endometrial microbiota affects clinical outcomes.